Available Technologies

Available Technologies
Inhibitors Of Histone Methyltransferase
Invention relates to the field of small molecule modulators. Particularly relates to the site specific inhibitors of histone methyltransferase and their preparation process. These compounds are isolated from pomegranate fruit and can be used as a lead compounds to develop anti-neoplastic or anti-HIV therapeutics.
	Status of Patent: US Granted patent
Modulators Of Histone Acetyltransferase
Invention relates to the field of novel anticancer agents. Particularly relates to the use of certain benzoic acid and benzamide compounds as modulators of enzymes histone acetyltransferases. These compounds are involved in gene expression and cancer and also such compounds are used for the treatment of diseases due to defects in gene regulation predominantly cancer.
	Status of Patent: US Granted patent
Modulators Of Histone Acetyltransferase
Invention relates to the field of novel anticancer agents. Compounds shown in figure are useful for the treatment of cancer, AIDS, HIV infections and asthma.
	Status of Patent: US Granted patent
Polyisoprenylated Benzophenones As Inhibitors Of Histone Acetyltransferases
Invention relates to Polyisoprenylated benzophenones and their isomers as inhibitors of histone acetyltransferases. These compounds are useful as biological switching molecules for evaluating the role of p300 and PCAF in cellular functions and also may be useful as new chemical entities for the development of anticancer drugs.
	Status of Patent: US Granted patent
Lutein from Oleoresin
Invention relates to a Process for isolating, purifying and formulating commercial grade lutein paste from oleoresin. Process comprises dissolving oleoresin in alcohol to obtain xanthophylls esters , hydrolyzing with base, quenching, drying ester layer and finally mixing the obtained lutein crystals with non water soluble fractions to obtain stable lutein paste. Lutein thus prepared can be made stable during storage without use of chemical additives and also available at viable prices.
	Status of Patent: US Granted patent
Preparation Process Of Chromium Dioxide And Other Oxides
Invention relates to a process for preparing chromium dioxide and other oxides of chromium. Hard sintered chromium oxide can be obtained without introducing any detectable impurity phase and the obtained chromium oxides and composites have shown significant negative magnetoresistance near room temperature. Chromium oxides have application in magnetic recording application.
	Status of Patent: US Granted patent
Preparation Process of an Intermediate Used in Synthesis of Atorvastatin
Invention relates to a impurity free preparation process of 4-fluoro-.alpha.-[2-methyl-1-oxopropyl]-y-oxo-n-beta-diphenylbenzenebutanamide, a key intermediate for the synthesis of Atorvastatin. Atorvastatin a drug useful for lowering blood cholestrol, stabilizing plaque and preventing stroke through anti-inflamatory and other mechanisms.
	Status of Patent: US Granted patent
Reusable Transition Metal Complex Catalyst for preparing 3,3�-Diaminobenzidine
Invention provides a reusable transition metal complex catalyst. Transition metal complex catalyst is useful for the preparation of high pure quality 3,3�-diaminobenzidine and its analogues. Tetraaminobiphenyl prepared using transition metal catalyst is a valuable intermediate for example used as a monomer in the preparation of polybenzimidazole polymers.
	Status of Patent: US Granted patent
Microfluidic Test Systems with Gas Bubble Reduction
Invention relates to a reservoir for use in testing a liquid as part of a microfluidic testing system includes testing chamber, a liquid inlet coupled to the testing chamber and a gas outlet. This system reduces or prevents the presence of gas bubbles and also can be utilized in a variety of testing regimes.
	Status of Patent: US Granted and Indian Patent Pending
System for Optically Analyzing a Substance
Invention relates to a microfluidic analysis system for optically analyzing a substance includes a light source having a plurality of selectable single-wavelength light sources, a substance presentation member optically coupled to the light source and an optical detection system. This system is less expensive, easy to transport and does'nt require large sample volumes.
	Status of Patent: US Granted and Indian Patent Pending
Microfluidic system utilizing thin-film layers to route fluid
System for microfluidic processing and analysis of samples includes a microfluidic device having a substrate and a thin-film layer formed on the substrate. This system allows analyzing samples in small volumes of liquids, providing more economical use of reagents and sample and also speeding assays.
	Status of Patent: US and Indian Patent Pending
Method and System for Shedding Load in Physiological Signals Processing
Invention relates to a method for shedding load in physiological signals processing includes steps of issuing a load shedding policy, transmitting the issued load shedding policy to device and discarding portions of the signal at device according to pattern until fraction of the signal is discarded. This system allows monitoring with significant power saving and reduced loss of detection quality.
	Status of Patent: US Granted and Indian Patent Pending
System for Diagnosis of Glycated Hemoglobin
Invention relates to a System for measuring glycated hemoglobin, comprises a microfluidic coupon, at least one capillary channel on the microfluidic coupon that encloses a solution capable of forming a solution density gradient, a sample well in connection with the capillary channel and configured for adding a sample containing red blood cells. This system obtains HbA1c levels which are red blood cells age specific and thus accurate diagnosis of diabetes.
	Status of Patent: US Granted and Indian Patent Pending Assistance given by IIPRD IIPRD Conducting Licensing Exercise for the Patent in India.
Tablet-In-Capsule Device for Programmed Drug Delivery System
Invention relates to a novel time dependent pulsed release system containing tablet in capsule for programmed release of drug for targeted delivery particularly salbutamol sulphate for the treatment of nocturnal asthama. Composition comprises impermeable capsule body and a soluble cap and at least two tablet formulations of which one is uncoated tablet comprising drug with pharmaceutical excipients that releases first pulse of drug as immediate release and another tablet that releases second pulse of drug as delayed release.
	Status of Patent: Indian Patent Pending
Herbal Compositions for Treatment of Inflammation and Arthritis
Invention relates to herbal composition for treatment of inflammation and arthritis comprising extract of at least one bioactive portion and/or powder of one or more medicinal herbs such as Sesbania grandiflora, Sesbania sesban and Terminalia chebula. This composition has no side effects, safe, has a long shelf life, inexpensive, and cost effective.
	Status of Patent: Indian Patent Pending
Pharmaceutical Compositions for Enhancement of Oral Bioavailability of Ester Prodrug
Invention relates to pharmaceutical formulation for enhancing the oral bioavailability of a prodrug ester as a non-aqueous formulation by formulating the ester prodrug such as Cefuroxime axetil with medium chain triglycerides. The prodrug is selected from antibiotics, corticosteroids, Non Steroidal anti-inflammatory drugs, Anti retroviral and Angiotensin II antagonists. The Preparation method is simple, cost effective, practical and reproducible for enhancement of the bioavailability.
	Status of Patent: Indian Patent Pending
Proliposomal Formulations for Cancer Therapy
Invention relates to site specific formulation for effective treatment of cancer. Proliposomal formulation for effective treatment of cancer comprises therapeutically effective amount of anticancer agent, phospholipids, cholesterol and coating polymer. The anticancer agent is paclitaxel , and the phospholipids are egg phosphatidylglycerol and distearoyl phosphatidylcholine.
	Status of Patent: Indian Patent Pending
Preparation of anhydrous rare earth metal halides
The invention relates to Preparation of anhydrous rare earth metal halides from their hydrates comprises preparing slurry of rare earth metal halide hydrate in an organic solvent, refluxing and azeotropic distillation for quantitative removal of surface and bond water. This prepared anhydrous rare earth metal halides particularly halides and more specifically anhydrous cerium chloride has wide range of applications in electrochemical reduction process for production of metal and as catalyst in the addition of organometallic to carbonyl group to form corresponding alcohols.
	Status of Patent: US and Indian Patent Pending Assistance given by IIPRD IIPRD Conducting Licensing Exercise for the Patent in India and US
Anti HIV: Bioactive Composition
Invention relates to bioactive composition and its preparation process comprising curcumin, cyprenone, ursolic acid, vinflunine, berberin sulfate and other additives like diluents, binder, disintegrants and lubricants. Composition safely and effectively removes the HIV antigen glycoproteins without any major side effects and also helps to control p17 and p24 antigen levels. Present composition can be used as a dietary supplement.
	Status of Patent: Patent Pending in South Africa, India, US, and EP Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent IIPRD Conducting Licensing Exercise for the Patent in India.
Plant Extract Composition for Liver dysfunction-Jaundice
Invention relates to the plant extract composition for treatment of liver dysfunction, jaundice and its processing steps of preparing the plant extract composition comprises extract of Curcuma longa, Phyllanthus emblica and Gymnosporea montana and carrier. The present composition exhibits superior activity in the treatment with no side effects.
	Status of Patent: Indian Patent pending Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent
Painless Treatment of Warts
The invention relates to Painless Treatment of dermatological conditions especially Warts, Corns & Callus comprising soluble sulphide of alkali or alkaline earth metals or their combination in solvents and eutectic mixture of Lidocaine and prilocaine in an oil in water emulsion. The sulfide component in the composition dissolves the hyperkeratotic epidermis and facilitates the penetration of the topical anesthetic component
	Status of Patent: Patent pending with positive ISR numbered PCT/IN2010/000001 Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent
Metal Nanosponges
The subject matter relates to a single step process for preparation of template and polymer free metal nanosponges having porous low density, high surface area, high gas permeability and thermal conductivity. Metal nanosponges are widely used in catalysis, fuel cells and membranes and as substrate for surface enhanced raman spectroscopy, as optical limiter and as antibacterial for purification/filtration of water.
	Status of Patent: Global Patent Pending Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent
Detection of Bacteremia
This invention relates to medical diagnostics for the detection of gram nature of pathogens in the blood with less detection time compared the present available technologies using unique PCR based detection process.
	Status of Patent: Indian Patent Pending Assistance given by IIPRD Conducted Preliminary Commercial Evaluation of the Product/Patent
Sterilisation of Male Condom
This technology is about sterilisation of Male condom using 60Co gamma ray irradiation and by which Urinary tract infection caused by the microbes present on the lubricants of condom can be prevented.
	Status of Patent: Indian Patent Pending Assistance given by IIPRD Conducted Preliminary Commercial Evaluation of the Product/Patent
Pathogen resistant transgenic plant
The technology relates to a pathogen resistant transgenic plant. Transgenic plant comprises a nucleic acid molecule of a pathogen, the nucleic acid molecule is homologous to a member selected from a group consisting of polynucleotide coding for a protein, a complementary sequence or the combination with a spacer nucleotide sequence.
	Status of Patent: Global Patent Pending Assistance given by IIPRD Conducted Commercial Evaluation of the Patent
Controlled Release formulations of anti-tubercular drugs
The subject matter relates to Microparticle-based drug delivery systems. More specifically, it relates to such drug delivery systems wherein the drug(s), preferably anti tubercular drugs are prepared in a Fixed Dose Combination in a manner to increase their bioavailability in the intestinal area by by-passing the gastric environment of the stomach. The present invention follows a novel approach by using pH sensitive polymers and specific targeting markers.
	Status of Patent: Indian Patent Applied For Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent IIPRD Conducting Licensing Exercise for the Patent targetting Medium Sized companies in Anti-Tubercular Market. Patent Being prosecuted Khurana & Khurana, Advocates and IP Attorneys
Tablets with Enhanced Dissolution Rate
The present technology provides tablets with enhanced dissolution rate of sparingly soluble drugs leading to increased bioavailability. Grains of solid dispersion of the drug in water soluble carrier are formed/cemented into tablets in a manner similar to that of cube sugar. Solid dispersions of drugs in carriers of poor compressibility can be easily formed into tablets of any suitable shape/size by known cube sugar technology. Resulting tablets are not only readily dispersible owing to capillary action but also ensure rapid dissolution of poorly soluble drug because of solid dispersion. Simultaneous exploitation of well-known approaches- solid dispersion, capillary action, optional surfactant and optional size reduction in the proposed technique results in steep enhancement of dissolution rate without compromising with content uniformity.
	Status of Patent: Indian Patent Granted Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent Patent Successfully Prosecuted till Grant Through Khurana & Khurana, Advocates and IP Attorneys
Pharmaceutical Nanoelastic Vesicular Systems
The present invention relates to non-ionic surfactant based nanoelastic vesicular systems comprising fluconazole or its pharmaceutically acceptable salts, solvates, enantiomers, polymorphs or mixtures thereof, processes for preparing the same and methods of use and treatment.
	Status of Patent: Indian Patent Pending Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent Complete Patent Protection Through Khurana & Khurana
Novel Controlled Release Tablet Of Poorly Soluble Drug
The subject matter relates to a novel attempt by the inventors to a controlled release dosage form for a range of poorly soluble drugs, especially, Carvedilol. The dosage form of the present invention uses a novel combination of solubilizer and a hrdrophilic swellable polymer to create a better and efficient controlled release formulation for poorly soluble drugs.
	Status of Patent: Indian Patent Pending Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent
Nano-Technology Based Herbal Topical Formulations
The patent pertains to the field of topical herbal formulations based on nano technology having therapeutic properties. The subjet matter relates to nano-emulsion based topical synergistic herbal formulations which are effective against acne and other skin disorder. More specifically, the present invention is concerned with the prophylactic and therapeutic topical treatment of skin disorders of all types of acne, eczema, psoriasis, aging, scaring and the like.
	Status of Patent: Worldwide Patent Pending Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent Executing the complete Licensing Exercise Worldover by Identifying, Negotiating and Closing the deal with one or more Potential Licensees
Antibiotic Fixed Dose Combination
Fixed Dose Combination of two antibiotics: cefepime hydrochloride (a cephalosporin) and amikacin sulphate (an aminoglycoside) administered as a single product. The product is developed to overcome multi bacterial, complicated hospital acquired ICU infections particularly in deadly diseases like Nosocomial Pneumonia and Febrile Neutropenia
	Status of Patent: Granted in India, South Africa, and South Korea. Patent Pending in multiple other geographies Assistance given by IIPRD Conducted Commercial Evaluation of the Product/Patent Executing the complete Licensing project in South African Market by Identifying, Negotiating and Closing the deal with a Potential Licensee
Delamination of Laminated Packaging Refuse
The invention relates to a process for recovery of useful constituents from multilayer laminated fragments arising as waste from industrial packaging manufacture. It relates more particularly to recovery of polyethylene plastic and aluminium foil from multilayered, laminated fragments containing these materials. According to the process disclosed, the delamination of the laminated constituents of the packaging waste fragments is carried out by keeping the fragments immersed in nitric acid of 50 - 70 % concentration at ambient temperature for 3 to 6 hour duration. The aluminium foils get fully separated from the plastics and the constituents remain in a submerged/floating condition. The delaminated constituents are removed from the nitric acid bath and allowed to pass through a series of bath for washing and separation of the materials. The fragments of separated aluminium foils and separated plastic are centrifuged to dryness and then allowed a sun bath for total drying. The separated fragments of aluminium foils can be used for producing aluminium ingots or sold as such. Similarly the separated fragments of plastic can be used for producing recycled plastic granules or sold as such. Click here for complete project presentation
	Status of Patent: Granted in India (IN 209755), Europe, Canada, and Israel. PCT Application No. PCT/IN2001/000218 Assistance given by IIPRD Conducted Freedom to Operate Search Conducted Patent Valuation Identification of Potential Licensees and Close to completing first round of negotiations with a Licensee
Biodegradable Polymer Composition
The invention disclosed in this application relates to a novel biodegradable additive polymer composition useful for the preparation of biodegradable plastic products which comprises of a mixture of (i) a polymer selected from Polyethylene, polypropylene, poly styrene, poly vinyl chloride or a mixture thereof (ii) Cellulose ( iii) Amides ( iv) nutrients selected from Blue green algae and / or Yeast and (v) Water. This composition can be mixed with a virgin polymer to get a master polymer. The master batch composition may be mixed with a virgin polymer, which is useful for preparing products which are biodegradable.
	Status of Patent: Patent Pending in India, United States, Europe, and other major geographies. PCT Application No. PCT/IN2007/000165 Assistance given by IIPRD Patent Valuation
Lime Stone and Navasar Based Multi-Purpose Composition
The present invention relates to a Lime Stone (Calcium Carbonate)and Navasar (Ammonium Chloride)Based Multi-Purpose Composition.
	Status of Patent: Patent Application Filed and Pending In India: Indian Application No. 1348/MUM/2007 Assistance given by IIPRD Commercial Evaluation and Cost/Feasibility Analysis Study Commercializing the Invention to Potential Licensees