Invention relates to Polyisoprenylated benzophenones and their isomers as inhibitors of histone acetyltransferases. These compounds are useful as biological switching molecules for evaluating the role of p300 and PCAF in cellular functions and also may be useful as new chemical entities for the development of anticancer drugs.
Status of Patent: US Patent 7402706
Technology relates to a Chemoenzymatic process for the stereoselective preparation of both (R) and (S) enantiomers of 3-hydroxy-3-phenylpropanenitrile, useful as a key intermediate for synthesis of (S)-Fluoxetine, (R)-Tomoxetine and cognant compounds.
Status of Patent: PCT Application WO/2002/057475, Granted Indian and UK Patent and pending JP Patent.
Invention relates to the field of novel anticancer agents. Compounds shown in figure are useful for the treatment of cancer, AIDS, HIV infections and asthma.
Status of Patent: US Patent 7332629
Technology relates to an inexpensive and extremely effective synthetic lung surfactant, which has the potential to save the lives of babies, children and adults suffering with any of a range of respiratory and lung ailments. Synthetic formulation consisting of a combination of phospholipids and synthetic peptides which may be administered in liquid form or nebulised/aerosolised.
Status of Patent: PCT Patent Application WO2011/104621
Invention relates to a process for preparation of nanocrystals of poorly water soluble drugs to increase the solubility and dissolution rate and bioavailability. It is an improved process for preparation of nanocrystals of lovastatin (LVS) to increase the solubility and dissolution rate and bioavailability. Lovastatin is a member of the drug class of statins, used for lowering cholesterol.
Status of Patent:Patent Pending in India No.1215/MUM/2011 Click here
Invention relates to a process for detecting the presence or absence of human hemoglobin HbAO and/or HbE in a sample by way of nanoparticle -hemoglobin interaction. Process for detecting the presence or absence of human hemoglobin HbAO and/or HbE in a sample comprises treating sample with copper nanoparticle, formation of moderate precipitate or aggregate indicating the presence of human haemoglobin HbE and the process has diagnostic ability to differentiate among proteins by the extent of their unfolding.
Status of Patent:Patent Pending in India No. 39/DEL/2011 Click here