Chemoenzymatic process for Stereoselective preparation of (R)-GABOB and Carnitine

Chemoenzymatic process for Stereoselective preparation of (R)-GABOB and Carnitine

Technology relates to a chemoenzymatic process for Stereoselective preparation of (R)-GABOB and Carnitine comprising tosylating 3,4-dihydroxybutanenitrile, resoluting racemic 3-hydroxy-4-tosyloxybutanenitrile and coverting the racemate to (R)-GABOB and Carnitine.
Status of Patent: US Patent 7816119 , Granted EP and Pending in India.