Pharmaceutical Compositions for Enhancement of Oral Bioavailability of Ester Prodrug

Pharmaceutical Compositions for Enhancement of Oral Bioavailability of Ester Prodrug

Invention relates to pharmaceutical formulation for enhancing the oral bioavailability of a prodrug ester as a non-aqueous formulation by formulating the ester prodrug such as Cefuroxime axetil with medium chain triglycerides. The prodrug is selected from antibiotics, corticosteroids, Non-Steroidal anti-inflammatory drugs, Anti-retroviral and Angiotensin II antagonists. The Preparation method is simple, cost effective, practical and reproducible for enhancement of the bioavailability.
Status of Patent: Indian Patent Pending