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Tablet-In-Capsule Device For Programmed Drug Delivery System

Invention relates to a novel time dependent pulsed release system containing tablet in capsule for programmed release of drug for targeted delivery particularly salbutamol sulphate for the treatment of nocturnal asthma. Composition comprises impermeable capsule body and a soluble cap and at least two tablet formulations of which one is uncoated tablet comprising drug with pharmaceutical excipients that releases first pulse of drug as immediate release and another tablet that releases second pulse of drug as delayed release.

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